Finalist of the last edition, Nice was surprised on the lawn of Le Puy (N, 0-1). Lucien Favre’s team was picked off by an early goal from Mohamed Ben Fredj whose low left shot at the entrance to the area deceived Kasper Schmeichel (3rd). Despite a strong domination of the Riviera in the second half, the Auvergnats held their feat, thanks to their goalkeeper Jonathan Millieras deflecting a shot from Kephren Thuram on his post (65th) and repelling a shot from Gaëtan Laborde (80th).
In Caen, the Nantes holder did not hesitate to qualify for the round of 16, by dismissing the fans of Vire (N3, 2-0) thanks to goals from Mostafa Mohamed (29th) and Evann Guessand (56th).
Opposed to Villerupt Thil (R1) in Amnéville, Annecy (L2) did not give details. Faced with amateurs quickly reduced to ten after the expulsion of Joachim Milla (32nd), the Savoyards rolled out (6-1), thanks in particular to a double from the experienced Vincent Pajot (6th, 29th).
Jostled by Granville (N2) who almost opened the scoring by Tony Théault stumbling over an excellent Jean Louchet (46th), Niort (L2) avoided the pitfall. Faced with Normans reduced to ten after the expulsion of their defender Guillaume Buon (59th), the Niortais showed realism to win 3-0, thanks to a double from Junior Olaitan (57th, 69th) and a goal by Yanis Merdji (77th).
Finally, Plabennec (N3) emerged victorious from the Breton derby against Vannes (N2, 2-0).